Reading all the posts in this thread I’d add more about my F150 experience. Before I start, I’m not arguing about the relative capability of ANY competing brand. To each his own. Nor about the F250 or F350. If my circumstances were different, I’d likely we in a 250, but I am very happy with my current 2019 F150.
My first F150 was a 2010 10.5 V8 6 speed and I towed a 26’ other brand via the southern route to Grand Canyon, north to Moab, then (to avoid Denver) south to SantaFe, then east to Memphis and home. That truck struggled frequently and did a lot of gear searching. I traded to a 2016 to get the lighter body and better mpg. The truck version was so new to the market the dealer didn’t have any literature about the engine choices, so I went with the 10L V8 6 speed. I soon regretted it as it performed only marginally better than the 2010, plus we were in the market for a bigger TT ( we succumbed to slideout envy). I traded for a 2018 3.5L ECOBoost 6 speed and loved that trucks road performance towing our new 35’ TT. Far superior to the prior V8s. But I got a great offer to trade for a 2019 F150, same basic truck, but with all the safety upgrades, especially blindspot while towing a trailer. Biggest improvement was the 10 speed trans with tow mode, which negated the concern for rear end gearing. We eventually went with our current 2022 3100RD for its lighter tongue weight and floor plan ( we love it). This truck/trailer combo now has over 20K miles together, traveling monthly throughout the eastern US far north to far south. I have used a SwapPro by BlueOx since 2018 after the dealer installed Ezlift failed on a trip with the 26’ TT.
My current setup was tuned-in to tow the TT and Truck level ( front of truck is less than 1/2” high). It did take a two inch rise ball to get the WDH set up. I feel nothing from 18 wheelers (I do feel box trucks slightly). Cross winds are not white knuckle. Mpg is 9-11 on highways. It takes 6-7% grades at speed up or down (very good engine braking, combined with tow mode maintains speed with minimal braking). I now enjoy steering correction comparable to when not towing. Emergency braking is excellent, by the way!! I just replaced tires and brakes at 89k on the truck. TT has GY Endurance replacing the OEM Westlakes.
Hope this helps someone.